Tena-Suck, Martha and Sánchez-Garibay, Carlos and Salinas-Lara, Citlaltepelt (2017) Intracranial Pleomorphic Malignant Fibrous Histiocytoma, Associated to Systemic Lupus Erythematous: A Case Report. British Journal of Medicine and Medical Research, 21 (9). pp. 1-9. ISSN 22310614
Suck2192017BJMMR32743.pdf - Published Version
Download (711kB)
Abstract
Background: Pleomorphic Malignant Fibrous histiocytoma (MFH) is a rare neoplasms of the soft tissue and bone composed of fibroblastic and histiocytic components with mitosis figures, nuclear pleomorphism and anaplasia.
Case Presentation: We presented a rare case of MFH in 44 year old woman with history of systemic erythematosus lupus and seizures. Treated with prednisone. The cerebral TAC showed a temporal mass. Craniotomy was performed and the examination of the biopsy sample revealed a giant, pleomorphic and atypical cells. Immunohistochemical analysis showed positivity for vimentin, CD68, Fascin, lysosyme and MIB-1 labeling index of 20%. Pleomorphic malignant fibrous histiocytoma was diagnosed, with involvement of the overlying temporal lobe. We report a case of MFH of the left temporal in adult.
Discussion: The neuroimaging and intra-operative opinion were of a meningioma. Histopathology, in conjunction with immunohistochemical evaluation and proliferation marker, confirmed the diagnosis. This is the firth case reported of PMFH associated to systemic lupus erythematous and different histological patterns.
Item Type: | Article |
---|---|
Subjects: | Souths Book > Medical Science |
Depositing User: | Unnamed user with email support@southsbook.com |
Date Deposited: | 19 May 2023 07:34 |
Last Modified: | 17 Oct 2024 04:22 |
URI: | http://research.europeanlibrarypress.com/id/eprint/793 |