Granisetron Versus Ondansetron for Prevention of Post-operative Nausea and Vomiting (PONV) in Patients Undergoing Laparoscopic Cholecystectomy

Naeem, Muhammad and Tabassum, Rafia and Khaskheli, Muhammad Saleh and Awan, Aijaz Hussain and Meraj, Munazzah and Irfan, Rao (2021) Granisetron Versus Ondansetron for Prevention of Post-operative Nausea and Vomiting (PONV) in Patients Undergoing Laparoscopic Cholecystectomy. Journal of Pharmaceutical Research International, 33 (54B). pp. 11-17. ISSN 2456-9119

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Abstract

Aim: To determine the efficacy of single dose Granisetron versus ondansetron in preventing PONV in patients undergoing elective laparoscopic cholecystectomy.

Methodology: A total of 100 patients were included in this study after the ethical approval of PUMHSW. Patients were randomly divided into two groups, in (Group G) 50 patients were given Granisetron and in (group O) 50 patients were given Ondansetron. Every patient was evaluated for PONV at one hour, two hours, three hours, six hours, twelve hours and 24 hours post operatively.

Results: A sample of 100 patients with age between 20-60 years (mean age 43.72±5.67 years), were included in this study. Patients were received granisetron 1 mg I/V and other patients received ondansetron 4mg I/V before induction.

Conclusion: we concluded that there was no significant difference between efficacy of granisetron and ondansetron as the p-value is found to be ≤0.05.

Item Type: Article
Subjects: Souths Book > Medical Science
Depositing User: Unnamed user with email support@southsbook.com
Date Deposited: 28 Feb 2023 07:59
Last Modified: 09 Jul 2024 08:24
URI: http://research.europeanlibrarypress.com/id/eprint/53

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