Tiwari, Pravish Kumar and Sathe, Padmakar (2010) Development and validation of HPTLC method for niacin and simvastatin in binary combination. Advances in Bioscience and Biotechnology, 01 (02). pp. 131-135. ISSN 2156-8456
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Abstract
A simple, sensitive and validated HPTLC method has been developed to determine Niacin and simvastatin simultaneously in synthetic mixture form. Chromatographic separation was achieved on a RP18 plate using a mixture of Methanol: Water: Acetic acid (60:40:0.1) at a wavelength of 237 nm. Linearity of themethod was found to be in the concentration range of 5000.0-25000.0 μg/ml for niacin and 100.0-500.0 μg/ml for simvastatin with correlation coefficient greater than 0.999. The method can be used for simultaneous determination of Niacin and Simvastatin.
Item Type: | Article |
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Subjects: | Souths Book > Biological Science |
Depositing User: | Unnamed user with email support@southsbook.com |
Date Deposited: | 01 Apr 2023 08:51 |
Last Modified: | 31 Jul 2024 13:58 |
URI: | http://research.europeanlibrarypress.com/id/eprint/485 |