Predictors of Mortality in Infective Endocarditis: A Retrospective Study

Boutgourine, Mina and Cherki, Assala and Bennajma, Kawtar and Massrioui, Joumana El and Jamili, Mohammed El and Karimi, Saloua El and Hattaoui, Mustapha El (2024) Predictors of Mortality in Infective Endocarditis: A Retrospective Study. Cardiology and Angiology: An International Journal, 13 (3). pp. 7-11. ISSN 2347-520X

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Abstract

Introduction: Infective endocarditis (IE) remains a major health problem with significant morbidity and mortality rates. Despite its serious implications, data on prognostic factors remain scarce.

Aim: We aim to determine predictive factors of mortality during infective endocarditis.

Methods: We performed a retrospective study including patients admitted to university hospital Mohammed 6 of Marrakech between September 2019 and January 2024 for a confirmed IE based on Dukes modified criteria.

Results: Of 43 patients included, 30 were males (69%) and 13 were females (30%). The mean age was 47.4 for men and 49.30 for women. 44.1% of our patients were admitted in heart failure, and 37% presented themselves late to our facility for management. Only 25.58% suffered from kidney failure and 55.8% presented an LV dysfunction. Complications were noted at a rate of 48%. Male’s group had less complication rate with 10% vs 38% in females’ group (p=0.042). And an overall mortality rate was at 34% and there were no significant sex related differences in terms of mortality between the two groups (33% in males vs 38% in females, p = 0.742).

The analytical study concluded that heart failure at admission(p<0.001), neurological complications(p=0.024), anemia (p=0.049), kidney failure (p=0.002), prolonged antibiotics (p=0.016), LV dysfunction (p=0.027) and an emergency surgery (p<0.001) were independent risk factors for mortality.

Conclusion: Our study underscores the urgent need to identify predictive factors of mortality in infective endocarditis (IE), and to adopt a multidisciplinary approach to enhance the care and management of patients, ultimately aiming to improve their survival rates.

Item Type: Article
Subjects: Souths Book > Medical Science
Depositing User: Unnamed user with email support@southsbook.com
Date Deposited: 12 Jun 2024 07:43
Last Modified: 12 Jun 2024 07:43
URI: http://research.europeanlibrarypress.com/id/eprint/1481

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