Kumar, Uma and Jain, Pooja and Singhal, Udita and Trivedi, Shalini (2023) Neurocutaneous Melanosis: A Diagnostic Challenge. JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 17 (1). ED07-ED09. ISSN 2249782X
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Abstract
Neurocutaneous Melanosis (NCM) is a rare congenital syndrome presenting as a large or multiple congenital melanocytic nevi and benign or malignant pigment cell tumours of the leptomeninges. The syndrome is defined as an error in the morphogenesis of the embryonal neuroectoderm. It is one of the rare phakomatoses seen in childhood and shows variable presentations. The authors hereby presents a case report of a 15-year-old male patient with NCM, who presented with recurrent episodes of seizures and difficulty in walking. On physical examination, the patient had multiple congenital cutaneous nevi on the trunk, back, and hands. Immunohistochemistry (IHC) with Haematoxylin & Eosin (H&E) staining confirmed the diagnosis of leptomeningeal diffuse melanocytosis was made.
Item Type: | Article |
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Subjects: | Souths Book > Medical Science |
Depositing User: | Unnamed user with email support@southsbook.com |
Date Deposited: | 13 Jun 2023 07:53 |
Last Modified: | 12 Sep 2024 05:02 |
URI: | http://research.europeanlibrarypress.com/id/eprint/1167 |